Piotr Spychalskia, Jarek Kobielaa, Magdalena Antoszewskaa, Agata Błażyńska-Spychalskaa, Barbara A. Jereczek-Fossac, Morten Høyerb
Hepatocellular carcinoma (HCC) is a raising condition world-wide. Most of patients are ineligible for surgery at diagnosis due to the advanced stage of the disease or poor medical condition of the patient. Charged particle therapy (CPT) is a radiotherapy modality showing promising results. The aim of this systematic review was to summarize current knowledge on patient-specific outcomes of CPT for HCC, including overall survival, local control, the effect of radiation dose and the toxicity burden (…)
Conclusions
CPT offers high local control, acceptable overall survival and low post-treatment morbidity. Quality of findings, especially on toxicities, is decreased by incomplete reporting and retrospective designs of available studies. Therefore, there is a strong need for better reporting and prospective studies.
https://www.thegreenjournal.com/article/S0167-8140(18)33651-X/fulltext
